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cholesterinised antigen
Cardiolipin to which cholesterol has been added.
(05 Mar 2000)
cholesterinosis
Synonym: cholesterolosis.
(05 Mar 2000)
cholesterinuria
Synonym: cholesteroluria.
Origin: cholesterin + G. Ouron, urine
(05 Mar 2000)
cholesteroderma
The occurrence of patches of yellow colour in the skin, resembling xanthoma, but without the nodules or plates.
Synonym: cholesteroderma, xanthochroia, xanthoderma, xanthopathy, yellow disease, yellow skin.
Origin: xantho-+ G. Chroma, colour
(05 Mar 2000)
cholesterol
1. <biochemistry> A pearly, fatlike steroid alcohol, C27H45OH, crystallizing in the form of leaflets or plates from dilute alcohol and found in animal fats and oils, in bile, blood, brain tissue, milk, yolk of egg, myelin sheaths of nerve fibres, the liver, kidneys and adrenal glands.
It constitutes a large part of the most frequently occurring type of gallstones and occurs in atheroma of the arteries, in various cysts and in carcinomatous tissue. Most of the bodys cholesterol is synthesised in the liver, but some is absorbed from the diet. It is a precursor of bile acids and is important in the synthesis of steroid hormones.
2. <chemical> A commercial preparation of cholesterol is used as a pharmaceutic aid.
Synonym: cholesterin.
Origin: Gr. Stereos = solid
(15 Jan 1998)
cholesterol 26-hydroxylase
<enzyme> Cyt p-450 dependent, ferredoxin involved
Registry number: EC 1.14.15.-
(26 Jun 1999)
cholesterol 7 alpha-monooxygenase
<enzyme> An enzyme that catalyses the hydroxylation of cholesterol to cholest-5-en-3 beta,7 alpha-diol.
Chemical name: Cholesterol,NADPH:oxygen oxidoreductase (7 alpha-hydroxylating)
Registry number: EC 1.14.13.17
(12 Dec 1998)
cholesterol cleft
A space caused by the dissolving out of cholesterol crystals in sections of tissue embedded in paraffin.
(05 Mar 2000)
cholesterol dehydrogenase
<enzyme> Converts cholesterol to coprostanol; mechanism given is incorrect for enzyme name
Registry number: EC 1.3.-
(26 Jun 1999)
cholesterol embolism
Embolism of lipid debris from an ulcerated atheromatous deposit, generally from a large artery to small arterial branches; it is usually small and rarely causes infarction.
Synonym: atheroma embolism.
(05 Mar 2000)
cholesterol ester storage disease
A rare benign adult form of inherited lysosomal lipid storage disease that is due to deficiency of acid lipase. It results in an accumulation of neutral lipids, particularly cholesterol esters, within cells (particularly leukocytes, fibroblasts, and liver cells). It is an allelic variant of wolman disease.
(12 Dec 1998)
cholesterol ester transport proteins
A protein that transports cholesterol esters from HDL to VLDL and LDL; a deficiency of this protein is associated with elevated HDL cholesterol.
(05 Mar 2000)
cholesterol esterase
<enzyme> An enzyme that catalyses the hydrolysis of cholesterol and some other sterol esters, to liberate cholesterol plus a fatty acid anion.
Chemical name: Steryl-ester acylhydrolase
Registry number: EC 3.1.1.13
(12 Dec 1998)
cholesterol esters
Fatty acid esters of cholesterol which constitute about two-thirds of the cholesterol in the plasma. The accumulation of cholesterol esters in the arterial intima is a characteristic feature of atherosclerosis.
(12 Dec 1998)
cholesterol monooxygenase
<enzyme> Multi-enzyme complex required for the conversion of cholesterol to adrenal cortex hormones. It releases methylpentanoate or isocaproaldehyde and pregnenolone. The complex contains cytochrome p-450, a flavoprotein, a non-haem iron protein, and NADPH.
Chemical name: Cholesterol,reduced-adrenal-ferredoxin:oxygen oxidoreductase (side-chain-cleaving)
Registry number: EC 1.14.15.6
(12 Dec 1998)
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