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hyperglobulinemic purpura
A condition characterised by proliferation of cells resembling lymphocytes or plasma cells in the bone marrow, anaemia, increased sedimentation rate and hyperglobulinaemia. Physical findings include mucosal bleeding, skin purpura and enlargement of the lymph nodes, liver and spleen.
(27 Sep 1997)
hyperglycaemia
<biochemistry> Too high a level of glucose (sugar) in the blood, a sign that diabetes is out of control.
It occurs when the body does not have enough insulin or cannot use the insulin it does have to turn glucose into energy. Hyperglycaemia may be seen in diabetes mellitus, Cushing's disease and Cushing's syndrome.
Signs of hyperglycaemia are a great thirst, a dry mouth, and a need to urinate often. For people with insulin-dependent diabetes, hyperglycaemia may lead to diabetic ketoacidosis.
Origin: Gr. Glykys = sweet, haima = blood
(09 Oct 1997)
hyperglycaemic hyperosmolar nonketotic coma
A syndrome consisting of extreme hyperglycaemia, serum hyperosmolarity and dehydration in the absence of ketosis and acidosis.
(12 Dec 1998)
hyperglycaemic-glycogenolytic factor
A polypeptide hormone (3485 D) secreted by the cells of the Islets of Langerhans in response to a fall in blood sugar levels. Induces hyperglycaemia. A family of structurally related peptides includes glucagon like peptides 1 & 2 (encoded by the same gene), gastric inhibitory polypeptide, secretin, vasoactive intestinal peptide, growth hormone releasing factor, pituitary adenylate cyclase activating polypeptide, exendins.
(18 Nov 1997)
hyperglycemia
<biochemistry> Too high a level of glucose (sugar) in the blood, a sign that diabetes is out of control.
It occurs when the body does not have enough insulin or cannot use the insulin it does have to turn glucose into energy. Hyperglycaemia may be seen in diabetes mellitus, Cushing's disease and Cushing's syndrome.
Signs of hyperglycaemia are a great thirst, a dry mouth, and a need to urinate often. For people with insulin-dependent diabetes, hyperglycaemia may lead to diabetic ketoacidosis.
Origin: Gr. Glykys = sweet, haima = blood
(09 Oct 1997)
hyperglyceridemia
Elevated plasma concentration of glycerides, which usually are present within chylomicrons; normal if transiently present after absorption of a meal containing lipids, abnormal if a persistent state.
Endogenous hyperglyceridemia, type IV familial hyperlipoproteinaemia or, more commonly, a nonfamilial sporadic variety.
Exogenous hyperglyceridemia, persistent hyperglyceridemia due to retarded rate of removal from plasma of chylomicrons of dietary origin; occurs in alcoholism, hypothyroidism, insulinopenic diabetes mellitus, types I and V hyperlipoproteinaemia, and during acute pancreatitis.
(05 Mar 2000)
hyperglycinaemia
Elevated plasma glycine concentration.
Ketotic hyperglycinaemia, an inherited metabolic defect which results from a deficiency of propionyl Coenzyme A carboxylase, the enzyme that converts propionate to methylmalonate; the enzyme requires biotin as a cofactor; clinically, affected infants have overwhelming illness, with lethargy, metabolic acidosis with ketosis, hypotonia; coma and seizures typically develop with early death; propionic acid is markedly elevated in plasma and urine; there is also hyperammonaemia, and elevated levels of other metabolites as well, include glycine, hence the original name for the syndrome.
Synonym: methylmalonic acidemia, propionic acidemia.
Nonketotic hyperglycinaemia, an inborn error of glycine metabolism, resulting from a defect in the glycine cleavage enzyme system; characteristically overwhelming disease in the newborn period, with coma, seizures and death, or, less often, gradual onset with failure to thrive, focal seizures, and mental retardation; there is massive elevation of plasma glycine, with increased levels in cerebrospinal fluid and urine; plasma hyperosmolality, severe dehydration occur without ketoacidosis; autosomal recessive inheritance.
(05 Mar 2000)
hyperglycinuria
Enhanced urinary excretion of glycine.
(05 Mar 2000)
hyperglycogenolysis
Excessive glycogenolysis.
Origin: hyper-+ glycogen + G. Lysis, loosening
(05 Mar 2000)
hyperglycorrhachia
Excessive sugar in the cerebrospinal fluid.
Origin: hyper-+ G. Glykys, sweet, + rhachis, spine
(05 Mar 2000)
hyperglycosaemia
<biochemistry> Too high a level of glucose (sugar) in the blood, a sign that diabetes is out of control.
It occurs when the body does not have enough insulin or cannot use the insulin it does have to turn glucose into energy. Hyperglycaemia may be seen in diabetes mellitus, Cushing's disease and Cushing's syndrome.
Signs of hyperglycaemia are a great thirst, a dry mouth, and a need to urinate often. For people with insulin-dependent diabetes, hyperglycaemia may lead to diabetic ketoacidosis.
Origin: Gr. Glykys = sweet, haima = blood
(09 Oct 1997)
hyperglycosuria
Persistent excretion of unusually large amounts of glucose in the urine; i.e., an extreme degree of glucosuria.
(05 Mar 2000)
hyperglyoxylaemia
Enhanced plasma (and possibly tissue) concentrations of glyoxylate; may develop during thiamine deficiency.
(05 Mar 2000)
hypergnosis
1. Projection of inner conflicts into the environment.
2. Exaggerated perception, such as the expansion of an isolated thought.
Origin: hyper-+ G. Gnosis, knowledge
(05 Mar 2000)
hypergonadism
A clinical state resulting from enhanced secretion of gonadal hormones.
(05 Mar 2000)
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