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fibromatosis, gingival
Generalised or localised diffuse fibrous overgrowth of the gingival tissue, usually transmitted as an autosomal dominant trait, but some cases are idiopathic and others produced by drugs. The enlarged gingiva is pink, firm, and has a leather-like consistency with a minutely pebbled surface and in severe cases the teeth are almost completely covered and the enlargement projects into the oral vestibule.
(12 Dec 1998)
fibromatous
Pertaining to, or of the nature of, a fibroma.
(05 Mar 2000)
fibromectomy
Removal of a fibroid tumour.
Synonym: fibromectomy.
Origin: fibroid + G. Ektome, excision
(05 Mar 2000)
fibrometer
An instrument that measures clot formation (as in tests for blood clotting in vitro) by mechanical detection of the clot by a moving probe.
(05 Mar 2000)
fibromodulin
<protein> A small proteoglycan, _60 kD, of the extracellular matrix. The core protein has a mass of _42 kD and is very similar to the core protein of biglycan and decorin. All three have highly conserved sequences containing 10 internal homologous repeats of _ 25 amino acids with leucine rich motifs. Fibromodulin has four keratan sulphate chains attached to N linked oligosaccharides.
(18 Nov 1997)
fibromuscular
Both fibrous and muscular; relating to both fibrous and muscular tissues.
(05 Mar 2000)
fibromuscular dysplasia
<radiology> Beaded segment of artery, medial type most common, F more than M, renal arteries, most common vessels, R more than L, mid and distal 1/3 (Differential diagnosis: atherosclerosis - ostium/proximal)
(12 Dec 1998)
fibromuscular hyperplasia
Thickening of arterial media by fibrosis and muscular hyperplasia, usually involving the renal arteries and causing multifocal stenosis and hypertension; a variety of fibromuscular dysplasia.
(05 Mar 2000)
fibromyalgia
<rheumatology> A disorder characterised by muscle pain, stiffness and easy fatigability. The cause is unknown and an estimated 3 million are affected in the USA.
(27 Sep 1997)
fibromyectomy
Excision of a fibromyoma.
(05 Mar 2000)
fibromyoma
<oncology, tumour> Benign uterine tumour also referred to as a uterine fibroid. Uterine fibroids can cause pelvic pain and irregular vaginal bleeding in some females.
(27 Sep 1997)
fibromyositis
Chronic inflammation of a muscle with an overgrowth, or hyperplasia, of the connective tissue.
Origin: fibro-+ G. Mys, muscle, + -itis, inflammation
(05 Mar 2000)
fibromyxoma
<tumour> A myxoma that contains a relatively abundant amount of mature fibroblasts and connective tissue.
Origin: fibro-+ G. Myxa, mucus, + -oma, tumour
(05 Mar 2000)
fibronectin
<protein> Glycoprotein of high molecular weight (2 chains each of 250 kD linked by disulphide bonds) that occurs in insoluble fibrillar form in extracellular matrix of animal tissues and soluble in plasma, the latter previously known as cold insoluble globulin. The various slightly different forms of fibronectin appear to be generated by tissue specific differential splicing of fibronectin mRNA, transcribed from a single gene. Fibronectins have multiple domains that confer the ability to interact with many extracellular substances such as collagen, fibrin and heparin and also with specific membrane receptors on responsive cells. Notable is the RGD domain recognised by integrins and two repeats of the EGF like domain. Interaction of a cells fibronectin receptors (members of the integrin family) with fibronectin adsorbed to a surface results in adhesion and spreading of the cell.
(18 Nov 1997)
fibronectin hexapeptide N-acetylgalactosaminyltransferase
<enzyme> Enzyme from foetal and malignant tissues recognizing the sequence val-thr-his-pro-gly-tyr in fibronectin
Registry number: EC 2.4.1.-
Synonym: udp-galnac-vthpgy alpha-galnac transferase, hexapeptide-galnac-transferase
(26 Jun 1999)
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