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fibronectin laminase
<enzyme> Fibronectin fragment which has been activated by calcium chloride to produce a calcium-dependent proteolytic activity that splits preferentially laminin and denatured collagen type 1; cleaves the ala-gly bond in the sequence gpagpr; the arginine residue in position p3' is important for this cleavage
Registry number: EC 3.4.99.-
Synonym: fn-laminase
(26 Jun 1999)
fibronectinase
<enzyme> Generated from a 27kda n-terminal heparin-binding fragment of fibronectin; calcium-dependent
Registry number: EC 3.4.21.-
(26 Jun 1999)
fibronectins
Glycoproteins found on the surfaces of cells, particularly in fibrillar structures. The proteins are lost or reduced when these cells undergo viral or chemical transformation. They are highly susceptible to proteolysis and are substrates for activated blood coagulation factor viii. The forms present in plasma are called cold-insoluble globulins.
(12 Dec 1998)
fibroneuroma
<oncology, tumour> A neurofibroma is a smooth, polypoid, soft or firm tumour that arises from the Schwann cells and fibroblasts of the neurilemmal sheath. They may grow anywhere in the myelinated nervous system.
(27 Sep 1997)
fibropapilloma
<tumour> A papilloma characterised by a conspicuous amount of fibrous connective tissue at the base and forming the cores upon which the neoplastic epithelial cells are massed.
(05 Mar 2000)
fibroplasia
Production of fibrous tissue, usually implying an abnormal increase of non-neoplastic fibrous tissue.
Origin: fibro-+ G. Plasis, a molding
(05 Mar 2000)
fibroplastic
Producing fibrous tissue.
Origin: fibro-+ G. Plastos, formed
(05 Mar 2000)
fibroplate
A plate or ring of fibrocartilage attached to the joint capsule and separating the articular surfaces of the bones for a varying distance, sometimes completely; it serves to adapt two articular surfaces that are not entirely congruent.
Synonym: discus articularis, articular disk, fibrocartilago interarticularis, fibroplate, interarticular fibrocartilage, intra-articular cartilage.
(05 Mar 2000)
fibropolypus
A polyp composed chiefly of fibrous tissue.
(05 Mar 2000)
fibroreticulate
Relating to or consisting of a network of fibrous tissue.
(05 Mar 2000)
fibrosarcoma
<oncology, tumour> Malignant tumour derived from connective tissue fibroblast.
(18 Nov 1997)
fibrose
To form fibrous tissue.
(05 Mar 2000)
fibroserous
Composed of fibrous tissue with a serous surface; denoting any serous membrane.
(05 Mar 2000)
fibrosing adenomatosis
A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Also, a benign nodular microscopic lesion of the prostate consisting of acimar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia.
Synonym: adenofibrosis, fibrosing adenomatosis, fibrosing adenosis.
(05 Mar 2000)
fibrosing adenosis
A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Also, a benign nodular microscopic lesion of the prostate consisting of acimar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia.
Synonym: adenofibrosis, fibrosing adenomatosis, fibrosing adenosis.
(05 Mar 2000)
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