aspartate |
<amino acid> A nonessential amino acid that plays a critical part of the enzyme in the liver that transfers nitrogen-containing amino groups, either in building new proteins and amino acids or in breaking down proteins and amino acids for energy and detoxifying the nitrogen in the form of urea. Depleted levels of aspartic acid may occur temporarily within certain tissues under stress, but, because the body is able to make its own aspartic acid to replace any depletion, deficiency states do not occur. Aspartic acid is abundant in plants, especially in sprouting seeds. In protein, it exists mainly in the form of its amide, asparagine. The popular sweetener Aspartame is a combination of aspartic acid and phenylalanine. Aspartic acid is considered nontoxic. (15 Nov 1997) |
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aspartate 1-decarboxylase |
<enzyme> A pyridoxal-phosphate protein that catalyses the alpha-decarboxylation of l-glutamic acid to form gamma-aminobutyric acid and carbon dioxide. The enzyme is found in bacteria and in invertebrate and vertebrate nervous systems. It is the rate-limiting enzyme in determining gaba levels in normal nervous tissues. The brain enzyme also acts on l-cysteate, l-cysteine sulfinate, and l-aspartate. Chemical name: L-Glutamate-1-carboxy-lyase Registry number: EC 4.1.1.15 (12 Dec 1998) |
aspartate 4-decarboxylase |
Aspartate beta-decarboxylase;a carboxy-lyase converting l-aspartate to l-alanine (releasing CO2); it decarboxylates aminomalonate and (in bacteria) removes SO2 from cysteinesulfinate. See: desulfinase. (05 Mar 2000) |
aspartate aminotransferase |
<enzyme> An enzyme catalyzing the reversible transfer of an amine group from l-glutamic acid to oxaloacetic acid, forming alpha-ketoglutaric acid and l-aspartic acid; a diagnostic aid in viral hepatitis and in myocardial infarctions. Synonym: aspartate transaminase, glutamic-aspartic transaminase, glutamic-oxaloacetic transaminase, serum glutamic-oxaloacetic transaminase. (05 Mar 2000) |
aspartate ammonia-lyase |
<enzyme> An enzyme that catalyses the conversion of aspartic acid to ammonia and fumaric acid in plants and some microorganisms. Chemical name: L-Aspartate ammonia-lyase Registry number: EC 4.3.1.1 (12 Dec 1998) |
aspartate carbamoyltransferase |
<enzyme> An enzyme that catalyses the conversion of carbamoyl phosphate and l-aspartate to yield orthophosphate and n-carbamoyl-l-aspartate. Chemical name: Carbamoyl-phosphate:L-aspartate carbamoyltransferase Registry number: EC 2.1.3.2 (12 Dec 1998) |
aspartate kinase |
<enzyme> An enzyme that catalyses the formation of beta-aspartyl phosphate from aspartic acid and ATP. Threonine serves as an allosteric regulator of this enzyme to control the biosynthetic pathway from aspartic acid to threonine. Chemical name: ATP:L-aspartate 4-phosphotransferase Registry number: EC 2.7.2.4 (12 Dec 1998) |
aspartate N-acetyltransferase |
<enzyme> Nervous system enzyme that mediates synthesis of n-acetylaspartic acid; utilises acetyl-CoA Registry number: EC 2.3.1.17 (26 Jun 1999) |
aspartate transaminase |
<enzyme> An enzyme of the transferase class that catalyses the reaction of l-aspartate and 2-ketoglutarate to yield oxaloacetate and l-glutamate. The enzyme is a pyridoxal phosphate protein. In the liver the reaction transfers excess metabolic nitrogen into aspartate for disposal in the urea cycle. Chemical name: L-Aspartate:2-oxoglutarate aminotransaminase Registry number: EC 2.6.1.1 (12 Dec 1998) |
aspartate-alpha-decarboxylase |
<enzyme> Forms beta-alanine Registry number: EC 4.1.1.11 Synonym: aspartate 1-decarboxylase (26 Jun 1999) |
aspartate-ammonia ligase |
<enzyme> An enzyme that catalyses the formation of asparagine from ammonia and aspartic acid, in the presence of ATP. Chemical name: L-Aspartate:ammonia ligase (AMP-forming) Registry number: EC 6.3.1.1 (12 Dec 1998) |
aspartate-saemialdehyde dehydrogenase |
<enzyme> An enzyme that catalyses the conversion of l-aspartate 4-saemialdehyde, orthophosphate, and NADP+ to yield l-4-aspartyl phosphate and NADPH. Chemical name: L-Aspartate-4-saemialdehyde:NADP+ oxidoreductase (phosphorylating) Registry number: EC 1.2.1.11 (12 Dec 1998) |
aspartate-trna ligase |
<enzyme> An enzyme that activates aspartic acid with its specific transfer RNA. Chemical name: L-Aspartate:tRNA-(Asp) ligase (AMP-forming) Registry number: EC 6.1.1.12 (12 Dec 1998) |
aspartic |
<chemistry> Pertaining to, or derived, asparagine; as, aspartic acid. Source: Websters Dictionary (01 Mar 1998) |
aspartic acid |
<amino acid> One of the twenty naturally occurring amino acids. Has the following chemical characteristics: pKa1 pKa2 pKa3 pI Water Solubility (30deg C)2.09-3.86 9.82 2.97 0.6 (09 Oct 1997) |