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cyclic guanosine monophosphate
A cyclic version of the nucleotide guanosine monophosphate. It plays a role in communicating vision from the eyes to the brain.
(09 Oct 1997)
cyclic haematopoiesis
An autosomal recessive, inherited immunodeficiency of gray collie dogs characterised by overwhelming recurrent bacterial infections, bleeding, and coat colour dilution.
Synonym: gray collie syndrome.
(05 Mar 2000)
cyclic imp
<chemical> Inosine cyclic 3',5'-(hydrogen phosphate). An inosine nucleotide which acts as a mild inhibitor of the hydrolysis of cyclic AMP and cyclic GMP and as an inhibitor of cat heart cyclic AMP phosphodiesterase.
Chemical name: Inosine, cyclic 3',5'-(hydrogen phosphate)
(12 Dec 1998)
cyclic inositol phosphate
1, 2 cyclic derivatives of inositol phosphatide that are invariably formed during enzymic hydrolysis of phosphatidyl inositol species. Have been proposed as second messengers in hormone activated pathways.
(18 Nov 1997)
cyclic neutropenia
Neutropenia recurring at regular intervals (14 to 45 days), in association with various types of infectious diseases, e.g., stomatitis, cutaneous ulcers, furuncles, arthritis, and others.
Synonym: cyclic neutropenia.
(05 Mar 2000)
cyclic nucleotide
A nucleoside monophosphate in which the phosphoryl group is linked twice to the sugar moiety; e.g., adenosine 3',5'-cyclic monophosphate (cAMP).
(05 Mar 2000)
cyclic nucleotide-regulated protein kinases
<enzyme> A group of enzymes that catalyses the phosphorylation of serine or threonine residues of proteins and is dependent on cyclic nucleotides.
Registry number: EC 2.7.10.-
(12 Dec 1998)
cyclic peptide
A peptide that forms a ring structure; e.g., tyrocidin A, an antibiotic, is a cyclic decapeptide; valinomycin is a cyclic depsipeptide.
(05 Mar 2000)
cyclic phosphate
An activator of phosphorylase kinase and an effector of other enzymes, formed in muscle from ATP by adenylate cyclase and broken down to 5'-AMP by a phosphodiesterase; sometimes referred to as the "second messenger." A related compound (2',3') is also known.
Synonym: cyclic adenylic acid, cyclic AMP, cyclic phosphate.
Acronym: cAMP
(05 Mar 2000)
cyclic phosphoric acid
In general, a linear polymer of phosphoric acid residues in pyrophosphate linkage in which the a and &omega; residues are similarly linked to make one endless loop or cyclic compound, specifically, a generic term applied to compounds in which one phosphoric acid residue is esterified to two hydroxyl groups of a single carbon chain, as in adenosine 3',5'-phosphoric acid, adenosine 2',3'-phosphoric acid, etc.
(05 Mar 2000)
cyclic phosphorylation
Any process in which a phosphatide ester forms a cylic diester by linkage to a neighbouring hydroxyl group.
(18 Nov 1997)
cyclic photophosphorylation
Process by which light energy absorbed by photosystem I in the chloroplast can be used to generate ATP without concomitant reduction of NADP or other electron acceptors. Energised electrons are passed from PS I to ferredoxin and thence along a chain of electron carriers and back to the reaction centre of PS I, generating ATP en route.
(18 Nov 1997)
cyclic strabismus
A strabismus that appears and disappears in rhythym, most frequently at 48-hour intervals.
(05 Mar 2000)
cyclic uridine 3',5'-monophosphate
A cyclic nucleotide involved in metabolic regulation; inhibits the growth of some tumours.
(05 Mar 2000)
cyclin
<protein> Proteins (A and B forms known) whose levels in a cell varies markedly during the cell cycle, rising steadily until mitosis, then falling abruptly to zero. As cyclins reach a threshold level, they are though to drive cells into G2 phase and thus to mitosis. Cyclins combine with p34 kinase (cdc2) to form maturation-promoting factor (MPF).
See: M phase promoting factor.
(18 Nov 1997)
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