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galactose-6-phosphate dehydrogenase
<enzyme> Possibly a ketoaldose, phosphorylated at primary alcoholic group; found in goat liver cytoplasm, requires nad, has high substrate specificity
Registry number: EC 1.1.1.-
Synonym: hexose-6-phosphate dehydrogenase
(26 Jun 1999)
galactose-6-phosphate isomerase
<enzyme> Converts galactose 6-phosphate to tagatose 6-phosphate
Registry number: EC 5.3.1.-
Synonym: galactose 6-phosphate isomerase, gal-6-p isomerase, tagatose-6-phosphate isomerase
(26 Jun 1999)
pantetheine 4'-phosphate
The prosthetic group of the acyl carrier protein in the fatty acid synthase complex.
Synonym: pantetheine 4'-phosphate.
(05 Mar 2000)
mannose-1-phosphate guanylyltransferase
<enzyme> A transferase that catalyses the transfer of GDP to the mannose of mannose-1-phosphate.
Consider also the bifunctional enzyme, phosphomannose isomerase-guanosine diphospho-d-mannose pyrophosphorylase; rfbm has similarity to long-chain, iron-containing alcohol dehydrogenases
Registry number: EC 2.7.7.13
Synonym: GDPmannose phosphorylase, GDP mannose pyrophosphorylase, GTP-alpha-d-mannose-1-phosphate guanylyltransferase, GDP-mannose pyrophosphorylase, rfbm gene product, rfbm protein
(26 Jun 1999)
mannose-6-phosphate
<biochemistry> Mannose derivative formed by phosphorylation in the Golgi complex of certain mannose residues on N glycan chains of lysosomal enzymes.
Believed to function as targetting signal that causes entry of these enzymes to the lysosomes. The receptor (215 kD) is enriched in specialised pre lysosomes.
(18 Nov 1997)
mannose-6-phosphate isomerase
<enzyme> An enzyme that catalyses the reversible isomerization of d-mannose-6-phosphate to form d-fructose-6-phosphate, an important step in glycolysis.
Chemical name: D-Mannose-6-phosphate ketol isomerase
Registry number: EC 5.3.1.8
(12 Dec 1998)
mannose-6-phosphate receptors
Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind.
(05 Mar 2000)
mannose-6-phosphate reductase
<enzyme> Involved in biosynthesis of mannitol in celery
Registry number: EC 1.1.1.224
Synonym: manp reductase
(26 Jun 1999)
geranylgeranyl phosphate kinase
<enzyme> Cytosolic enzyme that catalyses phosphorylation of geranylgeraniol phosphate to yield geranylgeranyl diphosphate; isolated from sulfolobus acidocaldarius
Registry number: EC 2.7.4.-
Synonym: ggp kinase
(26 Jun 1999)
vidarabine phosphate
<chemical> An adenosine monophosphate analog in which ribose is replaced by an arabinose moiety. It is the monophosphate ester of vidarabine with antiviral and possibly antineoplastic properties.
Pharmacological action: antimetabolites, antimetabolites, antineoplastic, antiviral agents.
Chemical name: 9H-Purin-6-amine, 9-(5-O-phosphono-beta-D-arabinofuranosyl)-
(12 Dec 1998)
glucose 1-phosphate
<biochemistry> Product of glycogen breakdown by phosphorylase. Converted to glucose 6 phosphate by phosphoglucomutase.
(18 Nov 1997)
glucose-1-phosphate adenylyltransferase
<enzyme> Shrunken-2 (sh2) protein is a subunit of this enzyme
Registry number: EC 2.7.7.27
Synonym: adpg synthetase, adpglucose pyrophosphorylase, ADP-glucose synthetase, shrunken-2 protein, shrunken gene product, ADP-glucose pyrophosphorylase, glgc gene product, bt2 gene product, brittle-2 gene product
(26 Jun 1999)
glucose-1-phosphate kinase
<enzyme> An enzyme that, in the presence of ATP, catalyses the phosphorylation of d-glucose 1-phosphate to form d-glucose 1,6-bisphosphate and ADP; found in yeast and muscle; d-glucose 1,6-bisphosphate is a required cofactor of one of the enzymes in glycogenolysis.
Synonym: glucose-1-phosphate kinase.
(05 Mar 2000)
glucose-1-phosphate phosphodismutase
A phosphotransferase catalyzing the reversible transfer of a phosphate residue from one d-glucose 1-phosphate to another, yielding d-glucose 1,6-bisphosphate and d-glucose. This enzyme provides a crucial intermediate needed for glucose-phosphate isomerase.
(05 Mar 2000)
glucose-1-phosphate uridylyltransferase
<enzyme> An enzyme that activates d-glucose by reacting d-glucose 1-phosphate with UTP, producing pyrophosphate and UDP glucose; a crucial step in glycogen biosynthesis.
(05 Mar 2000)
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