fibrination |
<medicine> The state of acquiring or having an excess of fibrin. Source: Websters Dictionary (01 Mar 1998) |
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fibrine |
Belonging to the fibres of plants. Source: Websters Dictionary (01 Mar 1998) |
fibrino- |
Fibrin. Origin: L. Fibra, fibre (05 Mar 2000) |
fibrinocellular |
Composed of fibrin and cells, as in certain types of exudates resulting from acute inflammation. (05 Mar 2000) |
fibrinogen |
<protein> Soluble plasma protein (340 kD, 46 nm long), composed of 6 peptide chains (2 each of A_, B_ and _) and present at about 2-3 mg/ml. (12 Nov 1997) |
fibrinogen-fibrin conversion syndrome |
<syndrome> A syndrome characterised by hypofibrinogenaemia with incoagulable blood; it may be seen in abruptio placentae, prolonged retention of a dead foetus in an Rh-isosensitised mother, haemolytic blood reactions, bilateral renal cortical necrosis, and cases of trauma. (05 Mar 2000) |
fibrinogenaemia |
An increased level of fibrinogen in the blood. Synonym: fibrinogenaemia. (05 Mar 2000) |
fibrinogenase |
<enzyme> Protease (34 kD) generated in blood clotting that acts on fibrinogen to produce fibrin. Consists of two chains, A and B, linked by a disulphide bond. B chain has sequence homology with pancreatic serine proteases: cleaves at Arg Gly. Thrombin is produced from prothrombin by the action either of the extrinsic system (tissue factor + phospholipid) or, more importantly, the intrinsic system (contact of blood with a foreign surface or connective tissue). Both extrinsic and intrinsic systems activate plasma factor X to form factor Xa which then, in conjunction with phospholipid (tissue derived or platelet factor 3) and factor V, catalyses the conversion. (18 Nov 1997) |
fibrinogenesis |
Formation or production of fibrin. (05 Mar 2000) |
fibrinogenic |
<physiology> Possessed of properties similar to fibrinogen; capable of forming fibrin. Pertaining to fibrinogen, producing fibrin. (12 May 2002) |
fibrinogenolysis |
The inactivation or dissolution of fibrinogen in the blood. Origin: fibrinogen + G. Lysis, dissolution (05 Mar 2000) |
fibrinogenopenia |
A concentration of fibrinogen in the blood that is less than the normal. Origin: fibrinogen + G. Penia, poverty (05 Mar 2000) |
fibrinogenous |
<physiology> Possessed of properties similar to fibrinogen; capable of forming fibrin. Pertaining to fibrinogen, producing fibrin. (12 May 2002) |
fibrinogens, abnormal |
Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilised fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenaemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing. (12 Dec 1998) |
fibrinoid |
1. Resembling fibrin. 2. A deeply or brilliantly acidophilic, homogeneous, refractile, proteinaceous material that: 1) is frequently formed in the walls of blood vessels and in connective tissue of patients with such diseases as disseminated lupus erythematosus, polyarteritis nodosa, scleroderma, dermatomyositis, and rheumatic fever; 2) is sometimes observed in healing wounds, chronic peptic ulcers, the placenta, necrotic arterioles of malignant hypertension, and other unrelated conditions. Origin: fibrin + G. Eidos, resemblance (05 Mar 2000) |