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lipofuscinosis
Abnormal storage of any one of a group of fatty pigments.
Ceroid lipofuscinosis, cerebral sphingolipidosis, late juvenile type.
Neuronal ceroid lipofuscinosis, a group of diseases characterised by accumulation of abnormal pigments in tissue (previously classified as cerebral sphingolipidoses). Major subtypes include chronic juvenile form (Batten disease), slowly progressive behaviour and visual symptoms, autosomal recessive inheritance; acute, late infantile form (Bielschowsky disease); autosomal recessive inheritance; chronic adult form (Kufs disease), variable inheritance; acute infantile form (Santavuori-Haltia disease), fulminating motor and mental deterioration often associated with myoclonic seizures. Minor forms have also been described.
(05 Mar 2000)
lipogenesis
The production of fat, either fatty degeneration or fatty infiltration; also applied to the normal deposition of fat or to the conversion of carbohydrate or protein to fat.
Synonym: adipogenesis.
Origin: Lipo-+ G. Genesis, production
(05 Mar 2000)
lipogenic
Relating to lipogenesis.
Synonym: adipogenic, adipogenous, lipogenous.
(05 Mar 2000)
lipogenous
Relating to lipogenesis.
Synonym: adipogenic, adipogenous, lipogenous.
(05 Mar 2000)
lipogenous diabetes
Diabetes and obesity combined.
(05 Mar 2000)
lipogranuloma
A nodule or focus of granulomatous inflammation (usually of the foreign-body type) in association with lipid material deposited in tissues, e.g., after the injection of certain oils.
See: paraffinoma.
Synonym: eleoma, oil tumour, oleogranuloma, oleoma.
(05 Mar 2000)
lipogranulomatosis
1. Presence of lipogranulomas.
2. Local inflammatory reaction to necrosis of adipose tissue.
Disseminated lipogranulomatosis, a form of mucolipodosis, developing soon after birth because of deficiency of ceramidase; characterised by swollen joints, subcutaneous nodules, lymphadenopathy, and accumulation in lysosomes of affected cells of PAS-positive lipid consisting of ceramide.
Synonym: Farber's disease, Farber's syndrome.
(05 Mar 2000)
lipohemia
An obsolete term for lipaemia.
(05 Mar 2000)
lipoic acid
<biochemistry> 1,2 dithiolane 3 valeric acid. Regarded as a coenzyme in the oxoglutarate dehydrogenase complex of the citric acid cycle. Involved generally in oxidative decarboxylations of _ keto acids. A growth factor for some organisms.
(18 Nov 1997)
lipoid
1. Resembling fat.
2. Former term for lipid.
Synonym: adipoid.
Origin: Lipo-+ G. Eidos, appearance
(05 Mar 2000)
lipoid granuloma
Granuloma characterised by aggregates or accumulations of fairly large mononuclear phagocytes that contain lipid.
(05 Mar 2000)
lipoid nephrosis
<nephrology> A disorder of the kidneys which largely affects the glomerulus, the blood filtering structure. This disorder is one common cause of nephrotic syndrome in children affecting 2 to 3 children per 100,000 population under age 16 in the us. Minimal change disease is also seen rarely in adults.
The cause is unknown but may be related to an autoimmune illness. Risk factors include a history for a immune disorder, recent immunisation or a bee sting.
Diagnosis is made by renal biopsy. Treatment include systemic corticosteroids which are usually quite effective in curing this disease. Other medications include chlorambucil and cyclophosphamide. In most cases, a moderate protein diet (1 gram protein per Kg body weight per day) will be recommended. Salt (sodium) restriction can be helpful to reduce swelling and vitamin D is usually supplemented.
(27 Sep 1997)
lipoid proteinosis
<disease> A familial disease occurring in the course of latent diabetes, marked by yellowish nodules due to deposits of a protein-lipid complex on the oral tongue and sublingual and faucial areas, translucent keratotic papillomatous eyelid lesions, keratotic lesions on the extremities, and hoarseness.
It is due to a disturbance of lipid metabolism with autosomal recessive inheritance and is frequently associated with intracranial calcifications.
inheritance: autosomal recessive.
Synonym: hyalinasis cutis et mucosae, lipoidosis cutis et mucosae, Urbach-Wiethe disease.
(05 Mar 2000)
lipoid theory of narcosis
That narcotic efficiency parallels the coefficient of partition between oil and water, and that lipoids in the cell and on the cell membrane absorb the drug because of this affinity.
Synonym: Meyer-Overton theory of narcosis.
(05 Mar 2000)
lipoidemia
<biochemistry> Presence of an abnormally high amount of lipid in the bloodstream.
Origin: Gr. Haima = blood
(18 Nov 1997)
MeSH(Medical Subject Headings) ˻ (http://www.nlm.nih.gov) : 5 : 7
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lipacidemia
(lip
ó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
lipaciduria
(lip
ó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
liparocele
(lip
ó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
lipase
(lip·ase) (lip¢[amacr]s, li¢p[amacr]s) 1. triacylglycerol lipase. 2. any enzyme that hydrolytically cleaves a fatty acid anion from a triglyceride or phospholipid.
ó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
lipasuria
(lip
ó: www.mercksource.com/pp/us/cns/cns_hl_dorlands.jspz...
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