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cytochrome c reductase
<enzyme> A flavoprotein containing iron. Cytochrome c may act as receptor. The enzyme reversibly catalyses the oxidation of NADH to NAD and reduced acceptor.
An inherited deficiency of this complex results in overwhelming acidosis.
Synonym: cytochrome c reductase.
Chemical name: NADH:(acceptor) oxidoreductase
Registry number: EC 1.6.99.3
(12 Dec 1998)
cytochrome reductase
<enzyme> A flavoprotein that catalyses the reduction of haem-thiolate-dependent monooxygenases and is part of the microsomal hydroxylating system. Its physiological acceptor is probably cytochrome p-450.
Chemical name: NADPH:ferrihemoprotein oxidoreductase
Registry number: EC 1.6.2.4
(12 Dec 1998)
HC toxin reductase
<enzyme> Nadph-dependent enzyme from maise which inactivates the cyclic tetrapeptide, hc toxin, from cochliobolus carbonum; amino acid sequence given in first source
Registry number: EC 1.-
Synonym: hm1 gene product
(26 Jun 1999)
progesterone 20-keto-reductase
<enzyme> Rat liver microsome enzyme requires NADPH to form the 20beta alcohol, also forms 20alpha oh using NADH
Registry number: EC 1.1.1.-
Synonym: progesterone 20-reductase, progesterone 20-beta reductase
(26 Jun 1999)
progesterone 5 alpha-reductase
<enzyme> Do not confuse this with progesterone reductase which is a 3 beta-hydroxysteroid dehydrogenase
Registry number: EC 1.3.1.30
(26 Jun 1999)
progesterone 5 beta-reductase
<enzyme> A stereospecific enzyme; forms 5 beta-pregnane-3,20-dione from progesterone; see also progesterone 5 alpha-reductase
Registry number: EC 1.3.1.-
(26 Jun 1999)
progesterone reductase
<enzyme> An enzyme that catalyses the reduction of a 3 beta-hydroxy-delta(5)-steroid to 3-oxo-delta(4)-steroid in the presence of NAD. It converts pregnenolone to progesterone and dehydroepiandrosterone to androstenedione.45.
Chemical name: 3 beta-Hydroxy-delta(5)-steroid:NAD+ 3-oxidoreductase
Registry number: EC 1.1.1.145
(12 Dec 1998)
sarcosine reductase
<enzyme> Involved in sarcosine metabolism in eubacterium acidaminophilum
Registry number: EC 1.4.4.-
Synonym: n-methylglycine reductase
(26 Jun 1999)
prostaglandin-E2 9-reductase
<enzyme> Catalyses reversibly an nad+ dependent oxidation of the 9alpha-hydroxyl group of 15-keto-13,14-dihydro-pgf2alpha to 15-keto-13,14-dihydro-pge2; also acts on pga1; sequence data indicates that it is identical with carbonyl reductase (NADPH) (EC 1.1.1.184)
Registry number: EC 1.1.1.189
Synonym: 9-ketoprostaglandin reductase, prostaglandin-9-hydroxydehydrogenase, pge2 9-ketoreductase, pge 9-ketoreductase, prostaglandin e2-9-oxoreductase, prostaglandin 9-ketoreductase, prostaglandin e2-9-ketoreductase, 9-hydroxy-pg dehydrogenase, 9-hydroxyprostaglandin dehydrogenase, pge2 9-reductase
(26 Jun 1999)
protein disulfide reductase (glutathione)
<enzyme> An enzyme that catalyses the reduction of a protein-disulfide in the presence of glutathione, forming a protein-dithiol. Insulin is one of its substrates.
Chemical name: Glutathione:protein-disulfide oxidoreductase
Registry number: EC 1.8.4.2
(12 Dec 1998)
heterodisulfide reductase
<enzyme> A two-subunit cytochrome b-containing enzyme from methanol-grown methanosarcina barkeri; catalyses the terminal step in the energy-conserving electron transport chain in methanogenic archaea; has been sequenced; authors give EC number as 1.99.4.- (not in enzyme nomenclature)
Registry number: EC 1.12.99.-
(26 Jun 1999)
xylulose reductase
<enzyme> An enzyme that reversibly converts xylulose to xylitol using either NADH (d-xylulose reductase) or NADPH (l-xylulose reductase); a deficiency of the l-form is seen in individuals with essential pentosuria.
Synonym: xylitol dehydrogenase.
(05 Mar 2000)
HMG CoA reductase inhibitor
Drugs, such as lovastatin and pravastatin, which interfere with the biosynthesis of cholesterol; used to treat hyperlipidemia.
(05 Mar 2000)
HMG-CoA reductase phosphatase
<enzyme> Similar to phosphoprotein phosphatase, EC 3.1.3.16
Registry number: EC 3.1.3.-
Synonym: 3-hydroxy-3-methylglutaryl coenzyme a reductase phosphatase
(26 Jun 1999)
selenate reductase
<enzyme> Terminal electron acceptor for anaerobic respiration in thauera selenatis; reduces selenate to selenite
Registry number: EC 1.97.-
(26 Jun 1999)
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